About The Forum
Calendar 2017 Poster Sessions : Automated Methods for Detection of Axon Bundle Activation in Epiretinal Prostheses
Student Name : Nandita Bhaskhar, Pulkit Tandon
Advisor : Subhasish Mitra
Research Areas: Computer Systems
Advisor : Subhasish Mitra
Research Areas: Computer Systems
Abstract:
Retinal prosthesis is an example of advanced electro-neural interfaces for treating blindness due to photoreceptor degeneration, which affects tens of millions of people worldwide. Epiretinal prostheses can produce more reliable visual percepts in blind patients via electrical stimulation of retinal ganglion cells (RGCs). Current epiretinal prostheses are prone to stimulation of axonal bundles, which relay the responses from 30-40 RGCs of different types to the brain. Indiscriminate stimulation of these bundles produces a signal that does not adhere to the natural neural code of the retina, and is known to significantly degrade quality of artificial vision in patients.
Our research aims to develop techniques in isolated retina for the design of advanced retinal prosthesis that delivers electrical stimuli more closely matched to the natural encoding of the retina. We use high-density multi-electrode arrays to electrically stimulate and record electrophysiological signals from primate retina.
We will discuss how we use these recordings to develop automated algorithms to determine whether an axon bundle has been activated, how it is validated and how it can be generalised to other Brain-Machine-Interfaces.
Bios:
Nandita Bhaskhar:
Nandita is an EE PhD candidate at Stanford (2014 - present), advised by Professor Subhasish Mitra and collaborating with Professor E J Chichilnisky. She works on Retinal Prosthesis for her research, which is right at the intersection of Electrical Engineering, Computer Science and Neuroscience. She has several interests that span a wide gamut of things - including but not restricted to Brain-machine-interfaces, IoT, Digital Health, Sensors, Circuits & Systems and their applications to widely diverse fields; travelling, art, creative writing, music, getting lost, hiking, biking and exploring new things.
Pulkit Tandon:
Pulkit is an EE PhD candidate at Stanford (2016 - present), advised by Professor Subhasish Mitra and collaborating with Professor E J Chichilnisky. He is working on Retinal Prosthesis and Nanosystems.
Retinal prosthesis is an example of advanced electro-neural interfaces for treating blindness due to photoreceptor degeneration, which affects tens of millions of people worldwide. Epiretinal prostheses can produce more reliable visual percepts in blind patients via electrical stimulation of retinal ganglion cells (RGCs). Current epiretinal prostheses are prone to stimulation of axonal bundles, which relay the responses from 30-40 RGCs of different types to the brain. Indiscriminate stimulation of these bundles produces a signal that does not adhere to the natural neural code of the retina, and is known to significantly degrade quality of artificial vision in patients.
Our research aims to develop techniques in isolated retina for the design of advanced retinal prosthesis that delivers electrical stimuli more closely matched to the natural encoding of the retina. We use high-density multi-electrode arrays to electrically stimulate and record electrophysiological signals from primate retina.
We will discuss how we use these recordings to develop automated algorithms to determine whether an axon bundle has been activated, how it is validated and how it can be generalised to other Brain-Machine-Interfaces.
Bios:
Nandita Bhaskhar:
Nandita is an EE PhD candidate at Stanford (2014 - present), advised by Professor Subhasish Mitra and collaborating with Professor E J Chichilnisky. She works on Retinal Prosthesis for her research, which is right at the intersection of Electrical Engineering, Computer Science and Neuroscience. She has several interests that span a wide gamut of things - including but not restricted to Brain-machine-interfaces, IoT, Digital Health, Sensors, Circuits & Systems and their applications to widely diverse fields; travelling, art, creative writing, music, getting lost, hiking, biking and exploring new things.
Pulkit Tandon:
Pulkit is an EE PhD candidate at Stanford (2016 - present), advised by Professor Subhasish Mitra and collaborating with Professor E J Chichilnisky. He is working on Retinal Prosthesis and Nanosystems.